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Piecemeal necrosis : ウィキペディア英語版 | Piecemeal necrosis
Piecemeal necrosis generally refers to a necrosis that occurs in fragments. ==Liver== When used in relation to the liver, ''piecemeal necrosis'' (also termed ''troxis necrosis'',〔 ''nibbling necrosis''〔 and ''interface necrosis'') refers specifically to a loss and degeneration of (limiting plate) hepatocytes at the lobular-portal-interface, producing a moth-eaten irregular appearance.〔(Pathbase > MPATH 597: cell and tissue damage process > MPATH 13: piecemeal necrosis ) Retrieved July 2, 2011〕 Piecemeal necrosis of the liver is associated with a lymphocytic infiltrate〔 into the adjacent parenchyma,〔(Transplant Pathology at the University of Pittsburgh > Chronic hepatitis > Chapter 3 > PATHOLOGIC FEATURES ) Last Modified: Mar 12, 2010〕 and with destruction of individual hepatocytes along the edges of the portal tract.〔 It is a feature of viral hepatitis (especially chronic hepatitis) as well as autoimmune hepatitis and steatohepatitis.〔
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